Thursday, 25 February 2016

Co-trimoxazole

Molecular Formula: C14H18N4O· 5 C10H11N3O3S
Molar Mass: 1556.71 g/mol

Co-trimoxazole
Chemical component Co-trimoxazole is usually prescribed for treating certain bacterial infections like pneumonia (a lung infection), bronchitis (infection of the tubes that are leading to the lungs) and infections of urinary tract, ears and also intestines. This chemical component also treats 'travelers' diarrhea. Combination of Trimethoprim and Sulfamethoxazole makes this component belong to a class of antibiotic medications called sulfonamides. This component works effectively by restricting the growth of bacteria and spreading infections to various part of body.

Chemical component is used for following conditions:
  • Prevention and treatment of pneumonia that is specially caused by the bacterium Pneumocystis jirovecii, previously known as Pneumocystis carinii (PCP). This type of infection is most common in people with decreased immune system function, for example due to HIV or AIDS
  • Prevention and treatment of toxoplasmosis
  • Treatment of lung bacterial infection known as nocardiosis
  • Infection of the bladder or tubes that pass urine also known as urinary tract infection
  • Flare-ups of chronic bronchitis due to bacteria
  • Middle ear infections called as otitis media

Sulfamethoxazole and Trimethoprim composed solution act on two different stages in the synthesis of bacterial folate, preventing the bacteria from producing folate. Without folate, the bacteria is not able to produce DNA and so are unable to increase in numbers. Co-trimoxazole therefore restricts the spread of infection

Some common effects with this powerful antibacterial component include rashes, itching, sore throat, fever or chills, severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps, shortness of breath, cough, unusual bruising or bleeding, yellowing of the skin or eyes, paleness, red or purple skin discolorations